CED Clinic
  • What to Expect
    • Your First Visit
    • Patient Intake Form
  • Services Offered
    • Telemedicine
    • Pediatric Patients
    • Additional Services
  • Registration Resources
    • Registration Help
    • Next Steps
    • Caregiver Information
    • Cannabis Control Commission
  • Contact
    • Contact the Clinic
    • Social Media Links
    • Meet The Team >
      • Meet Dr. Caplan
      • Meet Dr. Exelbert
  • CED Clinic Events
    • Upcoming Events
    • Fireside Chats
    • Dispensary Highlights
    • Past Events
  • Information and FAQ
    • CED Clinic Cannabis Care
    • Cannabis FAQ
    • Recommended Online Resources
    • CED Library
    • Printable Handouts >
      • Cannabis Journal
      • General Cannabis Info
      • Handouts for Illnesses >
        • Infectious Diseases
        • Mental Health
        • Skin Conditions
        • Neurological Disorders
        • Muscular and Skeletal Pain
        • Illnesses of Aging
        • Reproductive Health
        • Gastrointestinal Health
    • Awesome Extras! >
      • Vaporizing Overview
      • Unique Cannabinoids
      • MA Dispensary Map
      • Cannabis for Sleep
      • Topical Cannabis Products
      • Cooking with Cannabis
      • Cannabis Cookbook
  • Video Library
  • Massachusetts Dispensaries
  • Site Map
  • CED Blog

CED Blog

Use the search bar above to explore our blog articles! 

Benefits of cannabidiol on skin cells are compromised in psoriasis patients receiving UV irradiation treatment.

8/28/2020

0 Comments

 
Picture

Read More
0 Comments

The wide distribution of cannabinoid receptors in the gastrointestinal tract suggests cannabinoids like CBD can relieve GI pain

8/14/2020

0 Comments

 
Picture

Read More
0 Comments

Cannabidiol may enhance the effectiveness of immunotherapy in multiple myeloma

7/31/2020

0 Comments

 
Picture

Read More
0 Comments

Utilizing Cannabidiol in Psychiatric Disorders

5/11/2020

0 Comments

 
​S-adenosyl-L-methionine (SAMe), cannabidiol (CBD), and kratom in
 psychiatric disorders: Clinical and mechanistic considerations
In Summary
Researchers have recently unveiled the benefits and challenges of utilizing cannabidiol (CBD) in the treatment of psychiatric disorders. CBD has been FDA approved for rare epileptic disorders in the United States and has been recognized for its anxiolytic effects. Dosing CBD can be difficult due to various consumption methods, different products offering ratios of CBD: THC (tetrahydrocannabinol) and terpene contents, all of which cause different effects. Along with anxiolytic effects, the anti-inflammatory effects of CBD have also been well documented, acting through various biological mechanisms. Although THC may not be positively recognized for its psychoactive properties, CBD has been documented by major studies to have anxiolytic and antipsychotic effects with added neuroprotective and anticonvulsant effects. The author concludes that due to the minimal side-effects associated with CBD psychiatrists should seriously consider recommending CBD to patients. 
CBD has fallen into a more of a gray area than THC or cannabis in general as it appears to be widely accepted due to its wide availability yet some overarching associations still think poorly of its use. For example, the National Collegiate Athletic Association (NCAA) explicitly prohibits the use of THC and explains that, while not banned, student-athletes should be hesitant to use CBD products as it increases their risk of testing positive for THC and a healthy athlete should have no reason to utilize CBD anyway. Patients are recommended to seriously discuss their CBD use with a physician and do their research to determine how CBD is received by their places of work or other regulatory bodies they engage in. 
The study is available for review or download here:
Download & Review HERE
View more studies like this in the CED Foundation Archive:  http://bit.ly/drcaplan ​
0 Comments

The Effectiveness of Cannabidiol as an Anti-Epileptic

5/5/2020

1 Comment

 
Parasitic pharmacology- A plausible mechanism of action for cannabidiol
In Summary
A recent editorial questions the efficacy of utilizing cannabidiol (CBD) as an anti-epileptic and proposes a plausible mechanism of action for previously seen anti-epileptic effects. While discussing the issues within the two randomized-placebo controlled studies published in the New England Journal of Medicine (NEJM) that led to the eventual FDA approval of Edioplex for the treatment of seizures, the author raises concerns about the quality of content published by the NEJM. The author claims that the two studies claiming that CBD was a novel therapy for Dravets Syndrome and Lennox-Gastaut Syndrome did not examine or publish the pharmacokinetic properties of CBD within their study and that all benefits found were actually due to the drug-drug interaction between CBD and clobazam, a known anti-epileptic. As this hypothesis was only examined as a simulation further testing is needed.

​Cannabinoids, like all drugs, should continue to be questioned and retested for efficiency. Cannabis is not omnipotent and just because it holds promise for a myriad of ailments and disorders does not mean it may be the most efficient or ethical treatment available. Cannabinoids and terpenes deserve to be examined based on their potential as the medical community continues to search for novel cancer treatment, anti-emetics, appetite modulating drugs, and more which can then be fully developed for maximum pharmacological efficiency and compared to the current treatment. It seems irresponsible to not compare or develop cannabis-based medicine considering the promise seen in countless studies.

The study is available for review or download here:
Download & Review HERE
View more studies like this in the CED Foundation Archive:  http://bit.ly/drcaplan 
1 Comment

The Effect of Cannabidiol on Alcohol

4/3/2020

1 Comment

 
Picture
Effects of Cannabidiol on Alcohol-Related Outcomes- A Review of Preclinical and Human Research
In Summary
A review of preclinical research studies has revealed to possible beneficial effects of cannabidiol on alcohol-related outcomes. It was found that cannabidiol (CBD) is able to lessen alcohol consumption although the mechanism is not well understood. CBD may also protect consumers from the negative effects of alcohol use such as liver and brain damage. It is likely that CBD provides these protective effects through its modulation of inflammatory processes. It is recommended that further research is conducted in order to validate these findings and expand upon the knowledge of how CBD interacts with other common substances. 
​
As cannabis-based products become more widely accepted among the medical community and within society it is imperative that the interactions between cannabis and other drugs are known. Those who wish to use cannabis for certain ailments but are already on other medications may consume cannabis and experience negative side-effects due to the interaction of those drugs. Cannabinoids, terpenes, and flavonoids need to be modeled alongside other common medications so that physicians can safely recommend medications and so that pharmacists are able to accurately advise customers when they pick up prescriptions. Research is needed to ensure public safety in this time of evolving medications. 
The study is available for review or download here:
Download & Review HERE
View more studies like this in the CED Foundation Archive:  http://bit.ly/drcaplan 
1 Comment

    Archives

    April 2021
    March 2021
    February 2021
    January 2021
    December 2020
    November 2020
    October 2020
    September 2020
    August 2020
    July 2020
    May 2020
    April 2020
    March 2020
    February 2020
    January 2020
    December 2019
    July 2019

    Categories

    All
    Adolescent
    Alcohol
    Analgesic
    Antitumor
    Anxiety
    Athletes
    Australia
    Benzodiazepines
    Bioflavonoids
    Brain
    Breast Cancer
    Canada
    Cancer
    Cannabidiol
    Cannabinoid
    Cannabinoid Receptor 1
    Cannabinoid Receptor 2
    Cannabinoids
    Cannabis
    Cardiovascular
    CB1
    CB2
    CBD
    CBG
    CBN
    CBT
    Cessation
    Cholesterol
    Clinical
    Cognitive
    Cognitive Health
    Colorado
    Consumption
    Coronavirus
    COVID 19
    COVID-19
    Curcumin
    Cytokine-induced Killer Cells
    Decarboxylation
    Diet
    Dispensaries
    Drug Abuse
    ECS
    Edibles
    Endocannabinoid System
    Entourage Effect
    Epilepsy
    Fasciae
    Fatty Acid
    FDA
    Feline
    Female Reproductive System
    Females
    Flavonoids
    Football
    Gastroenterology
    Growing
    Heart Disease
    Hemp
    History
    Hospitalization
    Hypothermia
    Illicit
    Industry
    Inflammation
    Injury
    Israel
    Law
    Legalization
    Lung Cancer
    Male
    Marketing
    Massachusetts
    #MDTake
    Medical Cannabis
    Memory
    Mental Health
    Metabolomics
    Mice
    Microdosing
    Multiple Myeloma
    Multiple Sclerosis
    Musculoskeletal
    Myofascial Tissue
    Neurodegenerative Conditions
    Neurological
    Neuroprotective Effect
    NFL
    Nicotine
    Non-Cannabis Plant
    Norway
    Obesity
    Olfactory Ciruit
    Opioids
    Pain Relief
    Parkinson's Disease
    Pediatrics
    Pets
    Physical Activity
    Pregnancy
    Prenatal
    Psoriasis
    Psychiatric
    Psychosis
    PTSD
    Public Health
    Recreational Cannabis
    Relaxing
    Respiratory
    Saliva
    Schizophrenia
    Seizures
    Seniors
    Sexual Intercourse
    Skin
    Smell
    Smoking
    Spain
    Spinal Cord
    Sports
    Substance Abuse
    Synthetic
    Teratological
    Terpenes
    Tetrahydrocannabinol
    THC
    Therapy
    Tobacco
    Trauma
    UV Irradiation
    Vaping
    Young Adults

    RSS Feed

Home

Need Registration Help?

Services Offered

Dispensaries

Contact the Clinic

Copyright © 2018
  • What to Expect
    • Your First Visit
    • Patient Intake Form
  • Services Offered
    • Telemedicine
    • Pediatric Patients
    • Additional Services
  • Registration Resources
    • Registration Help
    • Next Steps
    • Caregiver Information
    • Cannabis Control Commission
  • Contact
    • Contact the Clinic
    • Social Media Links
    • Meet The Team >
      • Meet Dr. Caplan
      • Meet Dr. Exelbert
  • CED Clinic Events
    • Upcoming Events
    • Fireside Chats
    • Dispensary Highlights
    • Past Events
  • Information and FAQ
    • CED Clinic Cannabis Care
    • Cannabis FAQ
    • Recommended Online Resources
    • CED Library
    • Printable Handouts >
      • Cannabis Journal
      • General Cannabis Info
      • Handouts for Illnesses >
        • Infectious Diseases
        • Mental Health
        • Skin Conditions
        • Neurological Disorders
        • Muscular and Skeletal Pain
        • Illnesses of Aging
        • Reproductive Health
        • Gastrointestinal Health
    • Awesome Extras! >
      • Vaporizing Overview
      • Unique Cannabinoids
      • MA Dispensary Map
      • Cannabis for Sleep
      • Topical Cannabis Products
      • Cooking with Cannabis
      • Cannabis Cookbook
  • Video Library
  • Massachusetts Dispensaries
  • Site Map
  • CED Blog