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CED Blog

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Israeli Researchers Present First Clinical Evidence That Cannabis at Microdosing Levels Relieves Pain

5/24/2020

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(—)-β-Caryophyllene, a Terpine Found in Cannabis, Demonstrates Therapeutic Potential in a Mouse Model of MS

5/22/2020

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Community Trust Model of Cannabis Sales May Improve Public Opinion and Social Benefit of Cannabis Legalization

5/21/2020

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FDA hesitant to approve more CBD based products

5/20/2020

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Former NFL Quarterback urges athletes to consider CBD products

5/19/2020

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Will the Coronavirus force states to legalize marijuana?

5/18/2020

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​In Summary 
The ripple effects of COVID-19 in the United States is something even experts cannot predict. One of the only few things that can be agreed upon ths the financial revenue that will be lost. However, some individuals believe there is a way to help states and cities rebound after the pandemic: legalize recreational marijuana. The logic behind this is how regulating marijuana would be more effective than simply raising income taxes. If the latter happens, state representatives are fearful this will drive people out of the state if they cannot afford to live their anymore.
​
Many states who have not legalized medical and/or recreational marijuana are are looking at states such as Colorado as a model for a program to be implemented. In 2019 Colorado raised more than $300 million from marijuana sales. More populated states such as New York have the potential to earn well over half of a billion dollars just from recreational and medical cannabis. Although some states consider cannabis a taboo topic, economic hardships may force each state’s hands in hopes of economically bouncing back when the pandemic is over.

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Retired NFL player says cannabis saved his life ​

5/17/2020

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The Possible Effects of Cannabis Use in Adolescent Females

5/16/2020

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What Every Pediatric Gynecologist Should Know About Marijuana Use in Adolescents​
In Summary
A recent article has called for pediatric gynecologists to ward against the use of cannabis in adolescent females. By pointing out the inconsistent conclusions from multiple papers discussing the effect of cannabis use on neural development and fertility the author hopes to reduce the number of adolescent females utilizing cannabis. It is also pointed out that very little is known about the association between cannabis and mental health problems such as various forms of psychosis, anxiety, and depression. Considering how little conclusive evidence has been agreed upon by overarching associations of medical professions it does seem appropriate to warn against the risks of recreational cannabis but not without also acknowledging the possible benefits of medical cannabis. 

While there are many inconsistencies surrounding cannabis research some of the inconsistent conclusions can be heavily biased by funding parties. Biased articles are difficult to get around because they require fully delving into the material listed analyzed in the paper and looking into the studies that were included and left out of the meta-analysis to determine the validity of their findings. It is extremely frustrating to have articles presented to the public that are so heavily biased they cherry-pick data just to prove their side of a politically controversial therapy. Not all cannabis use is beneficial and is not well understood, but posting articles like this one give fodder to people attempting to prevent the rescheduling of cannabis so that specific chemicals can be harnessed for novel therapies to treat ailments we have no effective treatment for, such as Alzheimer’s, specific cancer types, and a slew of psychiatric disorders. Scientists have a responsibility to remain objective and this type of biased research is disappointing to come across.
The study is available for review or download here:
Click here for download
View more studies like this in the CED Foundation Archive:  http://bit.ly/drcaplan 
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More Research on Adolescent Cannabis Use and Mental Disorders

5/14/2020

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The persistence of the association between adolescent cannabis use and common mental disorders into young adulthood
In Summary
Further examination of chronic cannabis use in adolescents correlates with a higher prevalence of anxiety. Research discussing adolescent cannabis use and mental disorders has been inconsistent, mainly debating whether or not some mental disorders are caused by cannabis use. The featured article found no evidence of causation but did notice a positive correlation between chronic (described here as daily) adolescent cannabis use and the development of anxiety. The development of major depressive disorders was not positively correlated with cannabis use, even in regular users. Causation, especially for psychosis, should continue to be looked into in order to determine the full safety profile of cannabis-based medications. ​

Adolescent cannabis use does seem risky when considering that cannabis directly affects the brain while the brain is still developing and very few researchers have published well recognized and accepted data discussing the effect of cannabis on neural development. It seems interesting that chronic cannabis use is positively correlated to the development of anxiety when the most abundant non-psychoactive cannabinoid and multiple terpenes are praised for their anxiolytic effects. Research into the effect of each chemical component of cannabis should be researched to fully elucidate which cannabinoid or combinations of cannabinoids, terpenes, etc., cause alternations in neurodevelopment and other effects. ​
The study is available for review or download here:
Download and Review HERE
View more studies like this in the CED Foundation Archive:  http://bit.ly/drcaplan 
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Dysregulation of Fatty Acid Amide Hydrolase Correlates with Increased Obesity

5/13/2020

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The influence of the fatty acid amide hydrolase 385C_A single nucleotide polymorphisms on obesity susceptibility
In Summary
A recent study has revealed the positive correlation of fatty acid amine hydrolase (FAAH) polymorphisms with increased obesity rates in Iranian women. FAAH is a regulatory enzyme in the endocannabinoid system that is important for the inactivation of endogenous cannabinoids and has previously been associated with the obese phenotype. It was specifically found that two different genotypes of the 385 C/A polymorphism of FAAH increased the probability of obesity risk almost two times. Further research should focus on the possible screening of polymorphisms of the FAAH enzyme in order to advise those at an increased risk of developing obesity, and perhaps developing a weight management medication that targets FAAH and the endocannabinoid system. 

The “munchies” is a well-known side effect of cannabis consumption popularized by derogatory or humorous characterizations of chronic cannabis users, such as stoner/surfer Jeff Spicoli in Fast Times at Ridgemont High. Cannabinoids and terpenes have been shown to have various effects on weight management and appetite stimulation, including appetite suppression. Cannabis-based medication to aid in the recovery of anorexia nervosa are currently being researched due to the anxiolytic effects and appetite stimulation, but some terpenes like humulene have recently been featured for their appetite suppressant capabilities. Further research should be conducted to fully develop the various weight management medications that cannabis has the ability to produce. 
The study is available for review or download here:
Download and Review HERE
View more studies like this in the CED Foundation Archive:  http://bit.ly/drcaplan ​
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  • What to Expect
    • Your First Visit
    • Patient Intake Form
  • Services Offered
    • Telemedicine
    • Pediatric Patients
    • Additional Services
  • Registration Resources
    • Registration Help
    • Next Steps
    • Caregiver Information
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  • Contact
    • Contact the Clinic
    • Social Media Links
    • Meet The Team >
      • Meet Dr. Caplan
      • Meet Dr. Exelbert
  • Events and Calendar
    • Dispensary Highlights
  • Information and FAQ
    • CED Clinic Cannabis Care
    • Cannabis FAQ
    • Vaporizing Overview
    • Unique Cannabinoids
    • Recommended Online Resources
    • CED Library
    • Additional Cannabis Info >
      • General Cannabis Info
      • Guide - Sleep
      • Topical Cannabis Products
      • Cooking with Cannabis >
        • Cannabis Cookbook
    • Cannabis for Illnesses >
      • Gastrointestinal Health
      • Infectious Diseases
      • Mental Health
      • Skin Conditions
      • Reproductive Health
      • Neurological Disorders
      • Muscular and Skeletal Pain
      • Illnesses of Aging
  • Video Library
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    • Cannabis Journal
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