Clinical Takeaway In a controlled crossover trial of 25 healthy males, CBD at both low and high single doses showed no direct effect on cortical excitability compared to placebo, suggesting CBD alone...
Cannabinoid Clinical Trials: EEG Sleep Insomnia RCT
Clinical Takeaway In this small pilot trial of 20 insomnia patients, a single oral dose of 10 mg THC combined with 200 mg CBD reduced total sleep time compared to placebo, suggesting...
endocannabinoid system anxiety: cannabis flower vs edibles
Clinical Takeaway Cannabis use for anxiety relief shows different day-to-day effects depending on whether someone uses flower or edible products, and whether the product contains THC, CBD, or both. The type of...
Cannabidiol for Fibromyalgia: Evidence-Based Clinical Trial
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. These findings suggest that CBD should not currently be recommended...
endocannabinoid system clinical research: Eating Disorders
Clinical Takeaway A 15-year Canadian cohort study tracked adolescents into early adulthood to examine how early risk factors like body image concerns and disordered eating predict later outcomes including mental health conditions...
`Cannabinoid Clinical Trials: PTSD and Substance Use Meta-Analysis`
Clinical Takeaway People with PTSD and co-occurring substance use disorders who also use cannabis can still benefit meaningfully from trauma-focused treatments. Clinicians should not withhold or delay evidence-based PTSD care based on...
endocannabinoid system clinical research: Mobile Mental Health RCT
Clinical Takeaway A randomized controlled trial tested the Minder mobile app, co-developed with university students, to address mental health and substance use challenges during the high-risk transition period of higher education. Digital...
`Endocannabinoid System Research: Athletes & Mental Health`
Clinical Takeaway Retired professional athletes from high contact team sports show elevated rates of depression, anxiety, and other mental health challenges compared to the general population, with factors like concussion history, identity...
Endocannabinoid System Research: Cannabinoids in Pediatric Care
Clinical Takeaway Cannabinoids have been studied across a wide range of pediatric medical conditions, with existing evidence drawing from hundreds of studies including clinical trials and observational data. The research base is...
endocannabinoid system clinical research: Cannabis for Back Pain
Clinical Takeaway In this phase 3 trial of 820 adults, the full-spectrum cannabis extract VER-01 was evaluated against placebo over 12 weeks for chronic low back pain, with longer-term follow-up extending to...